Syros Pharmaceuticals, Inc. (SYRS) Stock Forecast & Price Prediction 2025, 2030, 2040, and 2050
Find Syros Pharmaceuticals, Inc. (SYRS) short-term stock forecasts for 2025 by month and long-term price predictions for 2025 to 2050. View past performance, analyst Buy, Sell or Hold ratings, and the latest SYRS stock news and headlines.
1 Month Prediction
$5.63 [4042.42%]
3 Month Prediction
$5.39 [3861.03%]
6 Month Prediction
$4.35 [3101.88%]
1 Year Prediction
$5.97 [4288.10%]
3 Year Prediction
$1.02 [650.31%]
5 Year Prediction
$1.00 [635.29%]
About Syros Pharmaceuticals, Inc.
Syros Pharmaceuticals, Inc. is a biopharmaceutical company that develops treatments for hematologic malignancies. The company's lead product candidates included tamibarotene, an oral selective retinoic acid receptor alpha (RARα) agonist, and SY-2101, an oral form of arsenic trioxide for treating acute promyelocytic leukemia.
The company was founded in 2012, and is based in Cambridge, Massachusetts.
Syros Pharmaceuticals, Inc. (SYRS) Historical Performance
IPO Date
Syros Pharmaceuticals, Inc. (NASDAQ:SYRS) went public on 06 July, 2016.
Change
Since inception, SYRS has decreased by 99.93%. In the last 5 years, SYRS has fallen from $84.30 to $0.14, a massive -99.84% decrease since 2020.
Historical Highs and Lows
In the past 5 years, the stock reached a high of $132.50 and a low of $0.14.
52 Week Range
$0.065
$6.928
The current price $0.14 is not near the 52-week extremes, which means that the stock is neither overbought nor underbought.
SYRS Stock Price History
Based on SYRS stock's historical price data, this table shows how the stock has performed in the last 6 years. Since 2019, the SYRS stock has fallen from $58.5 - $132.5 to $0.14 - $0.17, which is down -99.8%. Currently, the stock follows downward trend.
Here, we have calculated stock range of SYRS, indicating the highs and lows for each year, the average price based on the daily closing prices each year, and the change% from the average price.
| Year | Stock Price | Avg Price | Change% | Year Change |
|---|---|---|---|---|
| 2020 | $58.5 - $132.5 | $87.48 | 15.1 | 1 Year Change |
| 2021 | $32.6 - $109.45 | $58.75 | -22.7 | 2 Year Change |
| 2022 | $3.59 - $19.8 | $8.81 | -88.41 | 3 Year Change |
| 2023 | $2.49 - $7.79 | $3.88 | -94.9 | 4 Year Change |
| 2024 | $0.23 - $7.26 | $4.02 | -94.71 | 5 Year Change |
| 2025 | $0.14 - $0.17 | $0.15 | -99.8 | 6 Year Change |
SYRS Price Performance
6-Month Performance
SYRS stock dropped by 94.60% in the last six months.
1-Year Performance
The stock has trended downwards by 97.48% in the past year.
3-Year Performance
In the last 3 years, the stock has plummeted by 98.38%.
5-Year Performance
In the last 5 years, the stock has gone down by 99.84%.
According to Syros Pharmaceuticals, Inc.'s historical data, below graph gives us the exact picture of how the SYRS stock has performed year-over-year. Here, Each bar on the graph represents a particular year that illustrates how the stock's price changed from one year to the next.
YoY Performance
In the last five years, the stock has shown positive growth in 2 years and a decline in 3 years.
2020
57.02% ↑
2021
69.95% ↓
2022
88.99% ↓
2023
116.99% ↑
2024
97.05% ↓
NOTE: Green bars indicate that the stock has risen compared to the previous year, while red bars show that the stock has fallen.
Syros Pharmaceuticals, Inc. (SYRS) Financials & Stock Analysis
Total Revenue
Annual Revenue: $386.00 T (1Y)
Revenue for trailing 12 months decreased 96.12% year over year from 31st December, 2023.
If compared to the last 5 years, the revenue has gone down from $15.09 million to $386.00 thousand, a 97.44% change.
Market Capitalization
Syros Pharmaceuticals, Inc. has a market capitalization of $3.65M, which places SYRS in the nano-cap category.
Fundamental Analysis
EPS: $-0.16 (Q3), $-5.81 (1Y)
EPS decreased 72.88% since last quarter, and decreased 22.43% since last year.
Net Income: $-6.40 M (Q3), $-164.57 M (1Y)
Net Income decreased 72.58% since last quarter, and increased 73.87% since last year.
Free Cash Flow: $-20.69 M (Q3), $-109.98 M (1Y)
Free Cash Flow decreased N/A since last quarter, and decreased 11.53% since last year.
Below, we have listed 12 key indicators for Fundamental analysis for SYRS stock. These indicators help you understand Syros Pharmaceuticals, Inc.'s financial health, earnings and growth potential, and make a decision if the stock is a good long-term investment or not.
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Technical Analysis
Here, we have listed 5 key indicators for Technical Analysis for SYRS stock. These indicators help investors study past price movements and trading volumes to forecast future price changes, and find the right time when to buy, sell or hold the stock.
| Technical Indicators | Value |
|---|---|
| SMA20 | $0.14 |
| SMA50 | $0.18 |
| SMA200 | $2.27 |
| RSI | 36.25 |
| Beta | 1.31 |
SMA20 > Current Price
This signals SYRS stock is in short-term bearish momentum.
SMA50 > Current Price
This signals SYRS stock is in mid-term bearish momentum.
SMA200 > Current Price
This signals SYRS stock is in long-term bearish momentum.
Sentiment Based on Technical Analysis
Based on 8 technical analysis indicators, the overall sentiment for SYRS stock is Neutral. Out of all indicators, 2 indicates bullish signals, 3 signals bearish trends and 4 gives neutral trends. The SYRS stock forecast was last updated on 12 March, 2025.
Syros Pharmaceuticals, Inc. (SYRS) Stock Price Prediction and Forecast
According to short-term forecast, the stock is expected to rise to $8.31 by the end of 2025, and can reach around $13.27 to $9.40 in 2026. And, the long-term forecast suggests that the stock may further jump to $3.59 - $0.80 in 2028, and $1.69 - $1.61 by 2031. So, the SYRS stock shows a strong upward trend in the next several years.
Short-term SYRS Stock Price Prediction & Forecast
| Date | Forecasted Price | Change% |
|---|---|---|
| 2025-04 | $5.63 | 4039.71% |
| 2025-05 | $5.08 | 3635.29% |
| 2025-06 | $5.39 | 3863.24% |
| 2025-07 | $6.81 | 4907.35% |
| 2025-08 | $3.15 | 2216.18% |
| 2025-09 | $4.36 | 3105.88% |
| 2025-10 | $2.89 | 2025.0% |
| 2025-11 | $3.22 | 2267.65% |
| 2025-12 | $8.31 | 6010.29% |
In 2025, the SYRS stock price is expected to fluctuate between $2.89 and $8.31. According to the monthly forecast, the stock could rise to $8.31 by December 2024. If compared to the SYRS's current price, the stock could gain 6010.29% by the end of this year.
Long-term SYRS Stock Price Prediction & Forecast
| Year | Year Start | Year Mid | Year End | Change% |
|---|---|---|---|---|
| 2026 | $13.27 | $10.11 | $9.40 | 6811.76% |
| 2027 | $5.42 | $5.20 | $3.22 | 2267.65% |
| 2028 | $3.59 | $0.63 | $0.80 | 488.24% |
| 2029 | $2.74 | $1.16 | $1.75 | 1186.76% |
| 2030 | $1.45 | $1.35 | $1.36 | 900.0% |
| 2031 | $1.69 | $1.66 | $1.61 | 1083.82% |
| 2032 | $0.50 | $0.77 | $1.20 | 782.35% |
| 2033 | $0.58 | $0.71 | $0.45 | 230.88% |
| 2034 | $1.36 | $0.79 | $0.17 | 25.0% |
| 2035 | $0.41 | $0.36 | $1.03 | 657.35% |
| 2036 | $0.41 | $1.83 | $1.12 | 723.53% |
| 2037 | $0.97 | $0.87 | $0.93 | 583.82% |
| 2038 | $0.88 | $0.50 | $1.30 | 855.88% |
| 2039 | $1.67 | $0.53 | $0.41 | 201.47% |
| 2040 | $0.47 | $1.06 | $1.20 | 782.35% |
| 2041 | $1.60 | $0.23 | $0.92 | 576.47% |
| 2042 | $1.20 | $2.16 | $0.20 | 47.06% |
| 2043 | $0.14 | $1.38 | $1.18 | 767.65% |
| 2044 | $1.30 | $1.01 | $0.78 | 473.53% |
| 2045 | $1.44 | $1.14 | $1.38 | 914.71% |
| 2046 | $1.45 | $1.54 | $1.34 | 885.29% |
| 2047 | $1.54 | $1.09 | $0.02 | -85.29% |
| 2048 | $1.20 | $1.06 | $-0.13 | -195.59% |
| 2049 | $1.36 | $1.37 | $1.98 | 1355.88% |
| 2050 | $1.35 | $1.68 | $0.45 | 230.88% |
| 2051 | $0.14 | $0.59 | $0.99 | 627.94% |
Syros Pharmaceuticals, Inc. (SYRS) Stock Price Prediction & Forecast 2025
At the start of 2025, the SYRS stock was at $0.17. Today, it is trading at $0.14, which is -22.29% decrease from price at the beginning of the year. By the end of this year, you can expect the stock to reach to $8.31 by December 2025 with a 6010.29% change.
Syros Pharmaceuticals, Inc. (SYRS) Stock Price Prediction & Forecast 2026 - 2030
In the next five years, there will be a significant depreciation in the SYRS stock. During this period, the SYRS's price is forecasted to shift from $13.27 to $1.36, which is -89.75% loss.
In 2026, the stock would possibly open at $13.27, descends to $10.11 by mid-year, and wraps up at $9.40, reflecting a 6810.43% increase from today's price. Further moving to 2030, the stock can kick off the year at $1.45, drop to $1.35 by mid-year, and finish at $1.36, which is 898.95% change from current price.
Syros Pharmaceuticals, Inc. (SYRS) Stock Price Prediction & Forecast 2031 - 2040
During this period, the stock would move from $1.69 to $1.20, which is down 1080.21%
In 2031, we can expect SYRS to fluctuate between $1.61 and $1.69, a shift indicating a 1080.21% gain by year-end compared to current price. And Until 2040, SYRS can likely vary from $0.47 to $1.20. By the end of 2040, the stock could record a 781.29% rise from today's stock price.
Syros Pharmaceuticals, Inc. (SYRS) Stock Price Prediction & Forecast 2041 - 2050
According to long-term forecast, the SYRS stock can see an a downturn from $1.60 to $0.45 in this period. In 2041, the stock can experience a low of $0.23 by mid-year, closing the year at $0.92. This results in a 69.82% increase from today.
Moving towards the end of 2050, SYRS is projected to open the year at $1.35. The stock may peak to $1.68 during mid-year and finish the year at $0.45. Compared to the stock's current price, this translates to an overall gain of 230.80% by 2050.
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SYRS Competitors
| Ticker | Company | Market Cap | Price | 1m Change | Forecast |
|---|---|---|---|---|---|
| ARVN | Arvinas, Inc. | - | $8.30 | -53.11% ▼ | $409.53 ▲ |
| TNYA | Tenaya Therapeutics, Inc. | - | $0.46 | -54.95% ▼ | $790.53 ▲ |
| MRSN | Mersana Therapeutics, Inc. | - | $0.54 | 4.07% ▲ | $519.39 ▲ |
| XERS | Xeris Biopharma Holdings, Inc. | - | $4.13 | 7.83% ▲ | $41.7 ▲ |
| PSTV | Plus Therapeutics, Inc. | - | $1.44 | 97.26% ▲ | $70.11 ▲ |
Last updated Mar 12 at 7:45 PM
SYRS : Buy, Sell Or Hold?
Analyst Ratings
Sorry, No analyst ratings available for this stock.
Expert Analysis
According to SYRS short-term and long-term forecast, Syros Pharmaceuticals, Inc. shares are projected to go up by 230.88%, and reach a value of $0.45 per share by 2050.
As per technical analysis, indicators show a Neutral sentiment, while Fear & Greed Index stands at 42.857142857142854, which signals Fear. Also, SYRS has recorded 12/30 green days, which reflects a 57.14285714285714% positivity rate with a price volatility of 0.13%.
Plus, Price-to-Earnings (P/E) ratio of 0 suggests that SYRS stock is undervalued. So, Based on SYRS prediction and analysis, it may be the best time to hold SYRS stock right now.
Disclaimer: Stock predictions, forecasts and price targets provided for "SYRS” are solely for informational and educational purposes and should not be treated as investment or financial advice. Always conduct your own research or consider consulting with a financial advisor before making any investment decisions.